The MCB Brain Plast Conference is organised by a group of postdoctoral researchers at the CBBS ScienceCampus
and the Leibniz Institute for Neurobiology Magdeburg and supported by the scientific director of the LIN Eckart Gundelfinger as well as the head of science management and public relations, Constanze Seidenbecher.
"Combining behavioral, molecular and electrophysiological approaches, I investigate how stress experiences throughout the lifetime influence cognitive processes and how especially the GABAergic system contributes to stress resilience and vulnerability."
I work with presynaptic voltage-gated calcium channels and their accessory subunits. Using electrophysiological and imaging methods I currently investigate how the surface interaction of these subunits modulates calcium channels` localisation and function.
I am interested in learning mechanisms in the human brain. Therefore, I combine computational modeling of decision making processes with imaging techniques and electrophysiology.
I am heading the CortXplorer group at the Leibniz-Institute for Neurobiology in Magdeburg. It is our mission to better understand cognitively complex learning and decision processes in laboratory rodents at the level of interacting neuronal circuits. We focus on experience-dependent reorganizations of circuits in auditory cortex during acoustic learning.
I investigate cortical myelination in the living human brain using ultra-high field imaging at 7 Tesla. Using a combination of functional and structural mapping, I am interested how cortical myelin contributes to sensory and motor abilities, and their change over the life span.
Optical techniques are rapidly transforming systems neuroscience. Compared to previous methods they offer more selective stimulation and less invasive ways of recording from the brain. I'm using these optical methods, for example optogenetics and GECI imaging, to investigate monoaminergic brain circuits. These circuits are critically involved in a number of debilitating diseases and optical techniques are promising tools to better understand them and develop future treatments. In addition, I'm also focusing on the development of novel optical techniques and expand their use to other fields, for example neuroprosthetics.
Jeffrey Lopez Rojas
Synaptic transmission is just the beginning of a very complex process that finishes with a decision to fire or not fire an action potential. Action potential output is influenced not only by the excitatory drive a neuron receives, but also by the GABAergic inhibition and the intrinsic properties of the cell. My research interest is to study how intrinsic excitability of mature granule cells of the dentate gyrus is influenced by activity and neuromodulation and how those changes might impact mature cells role in learning and memory.
Kathrin Marter addresses the description of the Drosophila learning proteome with techniques that enable cell-type specific labeling, identification and visualization of the proteins that are newly synthesized after learning events in order to contribute to the formation of long-term memories.
"I am interested in adaptive and maladaptive stress responses and how they manifest on a molecular and behavioural level. In this context, I use classical and operant conditioning paradigms to model different aspects of psychiatric disorders."